Digital biomarkers for human physiology

The body isalways speaking.

HiiHealth transforms signals captured through everyday cameras and compatible wearables into meaningful measures of human physiology.

Measure what happens between the moments.

Continuous insight

Passive monitoring without relying on specialised equipment.

Preventive by design

Detect changes earlier, before symptoms.

Private by default

On-device processing with no face recording.

Our approach

Built from the
signal up.

Most wearable technologies translate signals into established measurements such as heart rate or oxygen saturation. HiiHealth takes a ground-up approach: we examine raw digital signals to discover underexplored physiological patterns and develop new biomarkers for health states that have not been easy or affordable to measure.

A new measurement layer between everyday life and traditional clinical testing.

HiiHealth signal portrait showing physiological data resolving from a human profile

Read the raw signal

Start with subtle changes in reflected light, movement, circulation, and autonomic activity.

Find new patterns

Use clinical insight and signal intelligence to identify physiology that established metrics may miss.

Build new biomarkers

Turn those patterns into repeatable measures for aspects of health that remain difficult to see.

Trusted science

Invisible signals.
Real outcomes.

Validated research, real-world outcomes, and insights designed to become useful before they become urgent.

Hydration

Hydration biomarker represented by a water droplet and fluid measurement rings

Understand fluid balance in real time.

Invisible signal / real insight

Early deterioration

Early deterioration biomarker represented by a clinical pulse signal

Detect clinical decline sooner.

Invisible signal / real insight

Biological age

Biological age biomarker represented by layered physiological growth rings

Measure aging at a physiological level.

Invisible signal / real insight

Passive signal → clear action.

Passive. Private. Powerful.

Your signal layer is always listening.

Passive camera-based sensing turns tiny changes in light, breath, and motion into a continuous picture of your physiology.

See how sensing works
Live signal

Physiological readiness

82

Stable

Hydration92%
Recovery76%
Stress32%

Platform

One signal layer.Multiple biomarkers.

A unified platform that understands the whole you—connecting patterns that are usually measured separately.

Hydration0%
Recovery0%
Stress0%
Respiration0 bpm
Full-body physiological signal visualization

Biomarker portfolio

Three research programs focused on physiology that changes continuously but is still measured only occasionally.

In development

Digital hydration biomarker

Understand how the body responds to fluid.

Hydration influences energy, cognition, circulation, sleep, and recovery, yet it is still commonly estimated through thirst, urine colour, or fluid intake. HiiHealth is developing a camera-based biomarker that analyses facial video signals to generate a fast, repeatable hydration score.

Designed to complement—not simply count—what a person drinks.

In development

Sepsis & critical-illness biomarker

See deterioration before obvious collapse.

Sepsis, severe infection, and dengue can worsen before conventional vital signs become clearly abnormal. In collaboration with frontline clinicians in Sri Lanka, we are evaluating microcirculatory, cardiovascular, and autonomic signals to support earlier risk stratification and escalation decisions.

DengueOS extends this work by connecting patient-level risk with community surveillance and public-health response.

In development

Digital biological-age biomarker

Make physiological ageing visible between tests.

HiiHealth is developing a camera-based digital proxy for ageing-related changes in vascular health, microcirculation, and autonomic function. The goal is repeatable tracking of how the body responds to sleep, exercise, nutrition, stress, and metabolic-health interventions.

A digital proxy designed to be calibrated against—not replace—validated biological and epigenetic-age tests.

Woman noticing subtle health signals in a quiet natural setting

Our belief

Better visibility changes what is possible: earlier understanding, calmer decisions, and more meaningful care.

We believe health should be understood earlier, more clearly, and more continuously.

Dr. Yudara Kularathne, founder and Chief Executive Officer of HiiHealth
Singapore · United States

Doctor. Engineer. Entrepreneur.

Medicine × AI × human physiology

Founder

Dr. Yudara Kularathne

Founder and Chief Executive Officer

Dr. Kularathne is a Consultant Emergency Physician, AI engineer, and healthcare entrepreneur working between Singapore and the United States. His career spans adult and paediatric emergency care, clinical leadership, engineering, and public health.

He has authored multiple patents in digital disease screening and biomarker development, founded HeHealth in 2022, and contributed to AI systems for infectious disease screening and primary care. His work has been recognised by the World Health Organization and other global bodies.

Today, he leads HiiHealth’s work at the intersection of frontline medicine, artificial intelligence, and continuous physiological measurement.

Consultant Emergency Physician
AI engineer and patent author
Founder of HeHealth
ATxSG Tech Leader of the Year

Partner with HiiHealth

Let’s build the next generation of health measurement.

We collaborate with organisations that can help validate, deploy, and scale clinically meaningful digital biomarkers—from healthcare institutions and research teams to public-health and technology partners.

Start a conversation

Validate

Clinical and academic studies that test biomarker performance in real settings.

Deploy

Care, wellness, and research workflows where continuous physiology can add value.

Scale

Technology, public-health, and distribution partnerships across diverse populations.

Questions.
Answered.

HiiHealth uses privacy-preserving camera-based sensing to read subtle changes in reflected light, breathing rhythm, and motion—without recording identifiable video.

Measurethe unseen.

Insight you can trust. Health you can act on. Join the first group to experience continuous physiological intelligence.